A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites
- Submitting institution
-
De Montfort University
- Unit of assessment
- 3 - Allied Health Professions, Dentistry, Nursing and Pharmacy
- Output identifier
- 3157
- Type
- D - Journal article
- DOI
-
10.1038/s42003-019-0520-5
- Title of journal
- Communications Biology
- Article number
- 271
- First page
- -
- Volume
- 2
- Issue
- 1
- ISSN
- 2399-3642
- Open access status
- Compliant
- Month of publication
- -
- Year of publication
- 2019
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
17
- Research group(s)
-
-
- Citation count
- 11
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- -
- Author contribution statement
- Several approaches and model system have been exploited for testing new drug which can inhibit the activity of Kynurenine-monooxygenase (KMO). In this study, I was involved in planning and carrying out the experiment conducted in Drosophila melanogaster (Fig 3a,b). This also include the analysis and the draft of the results
- Non-English
- No
- English abstract
- -