Clinical effectiveness and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the Comparison of LAser, Surgery and foam Sclerotherapy (CLASS) randomised controlled trial
- Submitting institution
-
Glasgow Caledonian University
- Unit of assessment
- 3 - Allied Health Professions, Dentistry, Nursing and Pharmacy
- Output identifier
- 41119841
- Type
- D - Journal article
- DOI
-
10.3310/hta19270
- Title of journal
- Health Technology Assessment
- Article number
- -
- First page
- 1
- Volume
- 19
- Issue
- 27
- ISSN
- 1366-5278
- Open access status
- Out of scope for open access requirements
- Month of publication
- April
- Year of publication
- 2015
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
21
- Research group(s)
-
-
- Citation count
- 43
- Proposed double-weighted
- Yes
- Double-weighted statement
- Foam sclerotherapy and endovenous laser ablation (EVLA) have emerged as alternative treatments to surgery for patients with varicose veins, but uncertainty exists regarding their effectiveness in the medium-longer term. This NHIR HTA study details a complex, parallel-group randomised controlled trial without blinding and economic modelling evaluation (n=798), conducted in eleven UK sites, resulting in a 165-page report. The objectives were to assess the clinical effectiveness and cost-effectiveness of foam, EVLA and surgery for the treatment of varicose veins. Andrew Elders conducted the statistical analyses, contributed to drafting the statistical methods, drafted the clinical effectiveness results, and reviewed the final manuscript.
- Reserve for an output with double weighting
- No
- Additional information
- -
- Author contribution statement
- Andrew elders made a substantial contribution to the design of the study, the analysis and interpretation of the study data, and critique the output for important intellectual content.
- Non-English
- No
- English abstract
- -