Impact case study database

The impact case study database allows you to browse and search for impact case studies submitted to the REF 2021. Use the search and filters below to find the impact case studies you are looking for.

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Enabling the discovery and development of AKT inhibitors as novel cancer therapeutics

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Submitting institution: Institute of Cancer Research: Royal Cancer Hospital (The)
Unit of assessment: 5 - Biological Sciences
Summary impact type: Technological
Request cross-referral to: -
Is this case study continued from a case study submitted in 2014?: Yes

1. Summary of the impact

2. Underpinning research

3. References to the research

4. Details of the impact

5. Sources to corroborate the impact

Additional contextual information

Grant funding

Grant number	Value of grant
C309/A2187	£22,500,000
95/A3/B/00415	£30,553
C576/A25	£1,498,807
C309/A8274	£29,156,418

Countries

UK
Netherlands
Argentina
Australia
Belgium
Canada
China
France
Germany
Hungary
Israel
Italy
Japan
South Korea
Peru
Poland
Russia
Spain
Taiwan
Brazil
Colombia
Czechia
Greece
India
Mexico
Philippines
Portugal
Saudi Arabia
South Africa
Sweden
Thailand
Turkey
Vietnam
Austria
Bulgaria
Chile
Slovakia
Switzerland

Formal partners

Friedrich Miescher Institute
Astex
AstraZeneca

Funding programmes

Cancer Research UK: Cancer Therapeutics Unit (CTU) grant (2001 to 2006)
Biotechnology and Biological Sciences Research Council: Structural and functional studies of SH2 domain-containing protein tyrosine phosphatases (Studentship)
Cancer Research UK: Molecular Basis for Control
Cancer Research UK: Cancer Therapeutics Unit (CTU) grant (2006 to 2011)

Global research identifiers

grid.11485.39
grid.418100.c

Name of funders

Cancer Research UK
Biotechnology and Biological Sciences Research Council

Researcher ORCIDs

0000-0001-8810-950X
0000-0003-1659-3034
0000-0002-3939-1673
0000-0002-8143-8498
0000-0003-1503-3123
0000-0001-8937-0873