Neuronal hyperactivity disturbs ATP microgradients, impairs microglial motility, and reduces phagocytic receptor expression triggering apoptosis/microglial phagocytosis uncoupling
- Submitting institution
-
University of Southampton
- Unit of assessment
- 5 - Biological Sciences
- Output identifier
- 18017356
- Type
- D - Journal article
- DOI
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10.1371/journal.pbio.1002466
- Title of journal
- PLoS Biology
- Article number
- e1002466
- First page
- -
- Volume
- 14
- Issue
- 5
- ISSN
- 1544-9173
- Open access status
- Compliant
- Month of publication
- May
- Year of publication
- 2016
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
25
- Research group(s)
-
-
- Citation count
- 81
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- -
- Author contribution statement
- Gomez-Nicola: My role involved the conceptualisation of the studies analysing the contribution of monocytes to the microglial population, investigation (surgical model of excitotoxicity, sample acquisition, sample analysis) as well as funding acquisition to support the studies conducted in Southampton. I also contributed to writing the paper.
- Non-English
- No
- English abstract
- -