A Work Flow to Build and Validate Patient Specific Left Atrium Electrophysiology Models from Catheter Measurements
- Submitting institution
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King's College London
- Unit of assessment
- 12 - Engineering
- Output identifier
- 97640596
- Type
- D - Journal article
- DOI
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10.1016/j.media.2018.04.005
- Title of journal
- Medical Image Analysis
- Article number
- -
- First page
- 153
- Volume
- 47
- Issue
- -
- ISSN
- 1361-8415
- Open access status
- Compliant
- Month of publication
- April
- Year of publication
- 2018
- URL
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- Supplementary information
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- Request cross-referral to
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- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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6
- Research group(s)
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-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Patient-specific cardiac computer models allow treatments to be optimised to each individual. Atrial fibrillation causes the properties of the atria to become heterogenous requiring models that have spatially varying material properties. In this paper we propose and apply the first clinical pacing protocol, signal processing and parameter inference methods to create and validate heterogenous material electrophysiology properties of 7 patients’ atria. This work supported a patent (20190298213), lead to the award of an ERC fellowship on atrial fibrillation and is now being developed into a clinical workflow for predicting patient response to catheter ablation supported by the EPSRC (EP/P01268X/1).
- Author contribution statement
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- Non-English
- No
- English abstract
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