Generation of ribosome imprinted polymers for sensitive detection of translational responses
- Submitting institution
-
University of Central Lancashire
- Unit of assessment
- 12 - Engineering
- Output identifier
- 19465
- Type
- D - Journal article
- DOI
-
10.1038/s41598-017-06970-x
- Title of journal
- Scientific Reports
- Article number
- 6542
- First page
- -
- Volume
- 7
- Issue
- -
- ISSN
- 2045-2322
- Open access status
- Compliant
- Month of publication
- July
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- 3 - Allied Health Professions, Dentistry, Nursing and Pharmacy
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
6
- Research group(s)
-
E - Centre for Smart Materials
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This research, in collaboration with the University of Surrey, was funded by the Leverhulme Trust (£164k; RPG-2014-267; Reddy co-PI). It was the first application of molecularly imprinted polymers for the biorecognition and sensitive and selective extraction of ribosomes from just 1000 cells; ribosome analysis is crucial to understanding gene regulation. It led to patent filing (GB1710353.2) and invitations to deliver two invited conference papers and one Keynote Lecture (Affinity 2017, Paris). This work has also led to new international collaborative funding in 2019/20 from the DAIWA Anglo-Japanese Foundation (13094/13096; AIST, Tsukuba, Japan) and The Royal Society (IES\R3\193093; Machakos University, Kenya).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
