A self-reporting tetrazole-based linker for the biofunctionalization of gold nanorods.
- Submitting institution
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University of Cambridge
- Unit of assessment
- 12 - Engineering
- Output identifier
- 7447
- Type
- D - Journal article
- DOI
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10.1002/chem.201502070
- Title of journal
- Chemistry
- Article number
- -
- First page
- 14309
- Volume
- 21
- Issue
- 41
- ISSN
- 1521-3765
- Open access status
- Out of scope for open access requirements
- Month of publication
- August
- Year of publication
- 2015
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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3
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Novel surface biofunctionalisation of nanomaterials was achieved with a surface linker that turns fluorescent upon reaction, significantly simplifying assessment of attached biomolecules on the surface. This eases the quantification of nanomaterial modification. Based on this work additional funding was secured; Sensor CDT PhD studentship funded by Medimmune (https://bit.ly/3e06wT7, grant 1946298) to develop DNA vaccine carriers, Cancer UK Primer Award (https://bit.ly/35H3dfB) to design senescent cell targeting nanocarriers, EPSRC IRC grant (https://bit.ly/34vN1yE) to explore design of drug nanocarriers, and HSFP grant (https://bit.ly/2HzgWNj) to use this chemistry for modification of neuronal implants. Additional impact was achieved by 2019 TEDx talk(https://www.youtube.com/watch?v=3QgJIuT33w0).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -