Effects of persistent atrial fibrillation-induced electrical remodeling on atrial electro-mechanics – insights from a 3D model of the human atria
- Submitting institution
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The University of Lancaster
- Unit of assessment
- 12 - Engineering
- Output identifier
- 238550385
- Type
- D - Journal article
- DOI
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10.1371/journal.pone.0142397
- Title of journal
- PLoS ONE
- Article number
- e0142397
- First page
- -
- Volume
- 10
- Issue
- 11
- ISSN
- 1932-6203
- Open access status
- Out of scope for open access requirements
- Month of publication
- November
- Year of publication
- 2015
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
5
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The development of the electromechanical model to study Atrial Fibrillation-Induced Electrical Remodeling (AFER) was the collaborative results of two EPSRC projects (EP/J009482/1-Lancaster University and EP/J009482/- Manchester University). This study provides novel insights into understanding atrial electro-mechanics illustrating that AFER impairs atrial contraction, which has attracted collaborations from clinical cardiologists from Taunton & Somerset Hospital, Manchester Royal Infirmary and Bristol University. The model has been continuously updated through ongoing collaboration with the above partners. The developed multiscale algorithm has also been used in a recent collaborative research on using micro-fibre composites sensors on drones with HEROTECH8 (edward.anastassacos@herotech8.com> and FleetUAS (James Dunthorne-james@fleetuas.com).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
