Can Simple Rules Control Development of a Pioneer Vertebrate Neuronal Network Generating Behavior?
- Submitting institution
-
University of Plymouth
- Unit of assessment
- 11 - Computer Science and Informatics
- Output identifier
- 905
- Type
- D - Journal article
- DOI
-
10.1523/jneurosci.3248-13.2014
- Title of journal
- Journal of Neuroscience
- Article number
- -
- First page
- 608
- Volume
- 34
- Issue
- 2
- ISSN
- 0270-6474
- Open access status
- Out of scope for open access requirements
- Month of publication
- January
- Year of publication
- 2014
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- 4 - Psychology, Psychiatry and Neuroscience
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
7
- Research group(s)
-
-
- Citation count
- 32
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This output reports pioneering research in computational neuroscience which enables a biologically realistic pair-wise connectivity in the spinal cord of the young tadpole to be identified. Our "developmental" approach combines neurobiological data with a new anatomical computer model: We "grow" axons in the spinal cord and create a synaptic contact at intersections of the growing axon and dendrites. Remarkably, when the connection architecture is projected to the functional model of spiking neurons the system demonstrates dynamics similar to swimming neural activity in experimental recordings. The model allows researchers to mimic experimental data on swimming initiation on skin stimulation.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
