Stability and cell uptake of calcium carbonate templated insulin microparticles
- Submitting institution
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Nottingham Trent University
- Unit of assessment
- 12 - Engineering
- Output identifier
- 84 - 1086453
- Type
- D - Journal article
- DOI
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10.1016/j.actbio.2013.11.011
- Title of journal
- Acta Biomaterialia
- Article number
- -
- First page
- 1423
- Volume
- 10
- Issue
- 3
- ISSN
- 1742-7061
- Open access status
- Out of scope for open access requirements
- Month of publication
- March
- Year of publication
- 2014
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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3
- Research group(s)
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A - Imaging, Materials and Engineering Centre
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This output develops a new approach to synthetize phagocytosis-resistant pure insulin particles. These particles have a controlled size, density and release performance that is indispensable to combat diabetes via pulmonary delivery. This idea formed the research basis for conception of the EU Horizon 2020 grant IMPAM (€160k). This new approach also led to a €40,000 contract with world-leading therapeutics company Sanofi-Aventis, project “Fabrication of nucleic acid delivery systems using CaCO3 nanoparticles”, contact kathrin.heermeier@aventis.com.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -