A Digital Preclinical PET/MRI Insert and Initial Results
- Submitting institution
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King's College London
- Unit of assessment
- 12 - Engineering
- Output identifier
- 98357761
- Type
- D - Journal article
- DOI
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10.1109/TMI.2015.2427993
- Title of journal
- Ieee Transactions on Medical Imaging
- Article number
- -
- First page
- 2258
- Volume
- 34
- Issue
- 11
- ISSN
- 0278-0062
- Open access status
- Out of scope for open access requirements
- Month of publication
- April
- Year of publication
- 2015
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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14
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- PET-MR is a promising imaging modality that offers to provide anatomical, functional, molecular and metabolic information of disease. However, current PET-MR scanners suffer from low spatial resolution and sensitivity, limiting their ability to detect disease early. This article describes the design and development of the first fully-digital pre-clinical PET-MR scanner that enables sub-millimetre spatial resolution and higher sensitivity than currently available PET-MR technology. The developed PET-MR system allows to assess cardiac function and glucose uptake with unprecedented image resolution and quality. The PET-MR technology was developed jointly with Philips Research (volkmar.schulz@pmi.rwth-aachen.de) that are at present considering commercialisation of the technology.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -