Controlled Release of C-Type Natriuretic Peptide by Microencapsulation Dampens Proinflammatory Effects Induced by IL-1β in Cartilage Explants.
- Submitting institution
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Queen Mary University of London
- Unit of assessment
- 12 - Engineering
- Output identifier
- 562
- Type
- D - Journal article
- DOI
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10.1021/bm501575w
- Title of journal
- Biomacromolecules
- Article number
- -
- First page
- 524
- Volume
- 16
- Issue
- 2
- ISSN
- 1526-4602
- Open access status
- Out of scope for open access requirements
- Month of publication
- January
- Year of publication
- 2015
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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6
- Research group(s)
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-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This work is developing microcapsule technologies to treat inflammation. Led to a successful ARUK grant (21210, £165K) for one PDRA and Rosetrees Trust Award (M486, £30K) for one PhD studentship and Wolfson Foundation (£5K) for one intercalated student. Published by the Royal Society of Chemistry (https://pubs.rsc.org/en/content/articlelanding/2020/NR/C9NR10329E#!divAbstract). One nomination (Berton Rahn research prize, AO Foundation), four press releases (https://www.sems.qmul.ac.uk/news/3387/can-a-protein-help-to-protect-osteoarthritic-joints-dr-tina-chowdhury-and-team-investigate; https://www.sems.qmul.ac.uk/news/5328/researchers-use-magnetism-to-keep-drugs-at-disease-sites; http://www.arthritisresearchuk.org/news/general-news/new-microcapsule-offers-potential-osteoarthritis-treatment-benefits.aspx), one film (https://www.youtube.com/watch?v=MOxhPNXfcT4&feature=c4-overview&list=UUD7C4mz9mrgkY4chpS419dQ), two patents (WO2011102809A1, US20180344650A1), two STEM engagements (https://www.sems.qmul.ac.uk/news/4996/fake-a-knee-at-the-science-museum; https://www.qmul.ac.uk/publicengagement/blog/2016/items/joints-in-space-outreach-at-the-festival-of-communities.html) and one podcast (https://www.bbc.co.uk/sounds/play/p077kmvf). The PDRA funded by this study was awarded a Lectureship at Sheffield Hallam University (https://www.shu.ac.uk/about-us/our-people/staff-profiles/nicholas-peake).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -