Intracellular pathways involved in bone regeneration triggered by recombinant silk-silica chimeras
- Submitting institution
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Nottingham Trent University
- Unit of assessment
- 12 - Engineering
- Output identifier
- 51 - 699392
- Type
- D - Journal article
- DOI
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10.1002/adfm.201702570
- Title of journal
- Advanced Functional Materials
- Article number
- 1702570
- First page
- -
- Volume
- 28
- Issue
- 27
- ISSN
- 1616-301X
- Open access status
- Compliant
- Month of publication
- September
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
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6
- Research group(s)
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A - Imaging, Materials and Engineering Centre
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- For silk-silica biocomposites, this paper provides the first evidence for the induction of key markers of osteogenesis in a silica concentration dependent fashion and further identifies how silica aids in the activation of specific integrins in contact with the mineral. The approach is viewed as a “particularly promising [system] for bone-tissue engineering applications” (doi:10.1038/s41578-020-0204-2) and “a milestone toward more efficient bioinspired material designs” (doi: 10.1126/sciadv.aax2805).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -