Biotransformation of Silver Released from Nanoparticle Coated Titanium Implants Revealed in Regenerating Bone
- Submitting institution
-
The Open University
- Unit of assessment
- 12 - Engineering
- Output identifier
- 1523898
- Type
- D - Journal article
- DOI
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10.1021/acsami.7b05150
- Title of journal
- ACS Applied Materials and Interfaces
- Article number
- -
- First page
- 21169
- Volume
- 9
- Issue
- 25
- ISSN
- 1944-8244
- Open access status
- Compliant
- Month of publication
- June
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
14
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This paper describes a key methodology for assessing the uptake/distribution of silver in tissue upon release from an implant. This novel study demonstrated that as nanoscale silver is readily ionised and bioavailable, there is no harmful effect of silver on bone formation. This is significant because silver-coated titanium surfaces inhibit biofilm production compared with non-coated structures, an important consideration in production of prosthetics for clinical orthopaedic applications.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
