A wireless smart patch for the controlled repetitive transdermal administration of therapeutic agents
- Submitting institution
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University of Ulster
- Unit of assessment
- 12 - Engineering
- Output identifier
- 78215103
- Type
- D - Journal article
- DOI
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10.1016/j.snb.2019.05.023
- Title of journal
- Sensors and Actuators B: Chemical
- Article number
- -
- First page
- 24
- Volume
- 294
- Issue
- -
- ISSN
- 0925-4005
- Open access status
- Compliant
- Month of publication
- May
- Year of publication
- 2019
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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3
- Research group(s)
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C - Biomaterials and Tissue Engineering
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Transdermal administration of therapeutic agents has largely been confined to passive, time release dosing regimens. Through a combination of a thermoresistive flexible heater, thermoresponsive encapsulation matrix and Bluetooth-controlled actuation, repeated active dosing has been successfully demonstrated. Augmenting existing advantages when compared to conventional oral and injection methods, the approach proffers patient controlled, fully automated, or indeed hybrid dosing regimens. As such, it can be envisioned that when combined with patient-specific data and/or inclusion of a feedback loop, the ability to enact bespoke, complex delivery profiles could be realised.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -