Tri-Needle Coaxial Electrospray Engineering of Magnetic Polymer Yolk-Shell Particles Possessing Dual-Imaging Modality, Multiagent Compartments, and Trigger Release Potential
- Submitting institution
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University of Ulster
- Unit of assessment
- 12 - Engineering
- Output identifier
- 77548107
- Type
- D - Journal article
- DOI
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10.1021/acsami.7b05580
- Title of journal
- ACS Applied Materials and Interfaces
- Article number
- -
- First page
- 21485
- Volume
- 9
- Issue
- 25
- ISSN
- 1944-8244
- Open access status
- Deposit exception
- Month of publication
- June
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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6
- Research group(s)
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C - Biomaterials and Tissue Engineering
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This significant work shows a facile method for engineering polymer based magnetic yolk-shell particles (YSPs) using electrospraying technique enabling dual-mode imaging capability (ultrasonic /magnetic resonance imaging) for multi-drug cargo systems via advanced single-step encapsulation. The presented facile engineering process supported by NSFC (2013 China) is valuable (with 3 granted patents, 1CN (CN104523431A) and 2US (10,828,263,2020 and 10, 828,263, 2020)) as synergistic micron-scaled platforms for sensitive pharmaceutical ingredients and contrast agents only deployable at ambient environments. The results were applied to a company to develop deep-lung pulmonary delivery system for chronic lung diseases.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -