Focused Ultrasound-Induced Cavitation Sensitizes Cancer Cells to Radiation Therapy and Hyperthermia
- Submitting institution
-
University of Dundee
- Unit of assessment
- 12 - Engineering
- Output identifier
- 56935098
- Type
- D - Journal article
- DOI
-
10.3390/cells9122595
- Title of journal
- Cells
- Article number
- 2595
- First page
- -
- Volume
- 9
- Issue
- 12
- ISSN
- 2073-4409
- Open access status
- Compliant
- Month of publication
- December
- Year of publication
- 2020
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- 1 - Clinical Medicine
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
5
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The output solves the long-term challenge of sonicating cell cultures in a reproducible way to study thermal and mechanical effects for drug uptake and radiation therapy support. This work is part of an international collaboration between The University of Dundee and the Innovation Center for Computer Assisted Surgery (ICCAS), University of Leipzig which developed the first 96 element transducer allowing individual sonication of each cell of a 96 well plate. Only through this large batch approach was the necessary high throughput screening possible.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -