Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors
- Submitting institution
-
University of Glasgow
- Unit of assessment
- 12 - Engineering
- Output identifier
- 12-12316
- Type
- D - Journal article
- DOI
-
10.1016/j.biomaterials.2020.120104
- Title of journal
- Biomaterials
- Article number
- 120104
- First page
- -
- Volume
- 252
- Issue
- -
- ISSN
- 0142-9612
- Open access status
- Compliant
- Month of publication
- September
- Year of publication
- 2020
- URL
-
http://eprints.gla.ac.uk/215696/
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
6
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The paper, an output of the UK Regenerative Medicine Platform (MR/L022710/1), introduced a new family of hydrogels with the potential to substitute Matrigel. The research enabled further funding from NC3Rs to develop an in vitro model of the bone marrow using these hydrogels (crack it challenge - https://nc3rs.org.uk/crackit/cleancut) and to develop substrates to grow mesenchymal stem cells with a mechanical passport (Leverhulme Trust 2019, https://www.leverhulme.ac.uk/listings?field_grant_scheme_target_id=13). The research was presented as an invited talk in the World Biomaterials Conference 2020 (https://virtual.wbc2020.org/session/fine-tune-of-cellular-behavior-from-fundamental-research-to-the-clinics).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
