An engineering approach to synthesis of gold and silver nanoparticles by controlling hydrodynamics and mixing based on a coaxial flow reactor.
- Submitting institution
-
University College London
- Unit of assessment
- 12 - Engineering
- Output identifier
- 10335
- Type
- D - Journal article
- DOI
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10.1039/c7nr04962e
- Title of journal
- Nanoscale
- Article number
- -
- First page
- 14149
- Volume
- 9
- Issue
- 37
- ISSN
- 2040-3364
- Open access status
- Compliant
- Month of publication
- September
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
3
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Nanoparticle synthesis is typically performed in batch reactors, but it suffers from poor reproducibility, which leads to inconsistent quality products. This work demonstrates a continuous flow method for synthesising metal nanoparticles applicable in healthcare, which is more robust and reproducible. By further understanding the mixing and mass transfer characteristics, the nanoparticle size and polydispersity can be precisely tuned. These are of critical importance to the quality of the final nanoparticle-based product (e.g., medical diagnostics, antimicrobial materials). This work led to a £2.5M EPSRC grant (EP/M015157/1) and an invited chapter in: Chemistry of Nanomaterials, De Gruyter, Berlin, 2019.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -