Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's Disease
- Submitting institution
-
University of Keele
- Unit of assessment
- 12 - Engineering
- Output identifier
- 412
- Type
- D - Journal article
- DOI
-
10.1016/j.chembiol.2017.07.014
- Title of journal
- Cell Chemical Biology
- Article number
- -
- First page
- 1205
- Volume
- 24
- Issue
- 10
- ISSN
- 2451-9456
- Open access status
- Compliant
- Month of publication
- September
- Year of publication
- 2017
- URL
-
https://www.sciencedirect.com/science/article/pii/S2451945617302726
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
7
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This EPSRC funded project (EP/P503981, EP/D066654/1, EP/K035193/1, EP/K00252X/1) exploited state-of-the-art x-ray techniques to examine the nanoscale sample chemistry of Alzheimer’s disease brain tissue. The paper supported the award of two EPSRC funded projects (EP/N033140/1, EP/N033191/1) and was a featured article on the Cell Chemical Biology website, receiving a preview article (Ayton et al. 2017) in the journal. Methodology developed in this work has resulted in numerous subsequent high-impact publications (Everett et al. Nanoscale, 2018, Brooks et al. Angewandte Chemie, 2020, Brooks et al. JTEMB, 2020). Components of this work were included in the successfully defended PhD thesis of James Everett.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
