A label-free biosensor based on graphene and reduced graphene oxide dual-layer for electrochemical determination of beta-amyloid biomarkers
- Submitting institution
-
University of Plymouth
- Unit of assessment
- 12 - Engineering
- Output identifier
- 1831
- Type
- D - Journal article
- DOI
-
10.1007/s00604-020-04267-x
- Title of journal
- Microchimica Acta
- Article number
- 288
- First page
- -
- Volume
- 187
- Issue
- 5
- ISSN
- 0026-3672
- Open access status
- Compliant
- Month of publication
- -
- Year of publication
- 2020
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
5
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Graphene biosensors have the potential to provide sensitive, minimally invasive, and cost-effective biomarker detection techniques for disease diagnosis. The novelty of this paper is that it reports the development of a label-free technique for the detection of beta-amyloid biomarkers, an important blood biomarker of Alzheimer's disease, using graphene-based biosensors with improved sensitivity and reproducibility. This is one of the key discoveries of the EU BBDiag project for the development of blood biomarker-based diagnostics for Alzheimer's disease.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
