Using argument notation to engineer biological simulations with increased confidence
- Submitting institution
-
University of Sunderland
- Unit of assessment
- 11 - Computer Science and Informatics
- Output identifier
- 977
- Type
- D - Journal article
- DOI
-
10.1098/rsif.2014.1059
- Title of journal
- Journal of the Royal Society Interface
- Article number
- 20141059
- First page
- -
- Volume
- 12
- Issue
- 104
- ISSN
- 1742-5689
- Open access status
- Out of scope for open access requirements
- Month of publication
- March
- Year of publication
- 2015
- URL
-
http://sure.sunderland.ac.uk/id/eprint/10842/
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
5
- Research group(s)
-
-
- Citation count
- 11
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This paper formed the basis of a commercial tool, Reason, sold by Simomics Ltd, https://www.simomics.com/offerings (Reason). Reason is used by a global company to support a structured argumentation approach, inspired by safety critical engineering, to deliver a hypothesis-based model formulation and risk assessment to reduce animal experimentation. Work also underpinned the development of Virtual Fish Laboratory with AstraZeneca (again by Simomics) which itself is now the technical backbone of a funded Innovative Medicines Initiative programme for 6 years starting Sept. 2020 involving major pharmaceutical companies https://imi-premier.eu/.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -