Methodology to estimate the break force of pharmaceutical tablets with curved faces under diametrical compression
- Submitting institution
-
The University of Leicester
- Unit of assessment
- 12 - Engineering
- Output identifier
- 1538
- Type
- D - Journal article
- DOI
-
10.1016/j.ijpharm.2018.10.014
- Title of journal
- International Journal of Pharmaceutics
- Article number
- -
- First page
- 399
- Volume
- 554
- Issue
- -
- ISSN
- 0378-5173
- Open access status
- Compliant
- Month of publication
- October
- Year of publication
- 2018
- URL
-
-
- Supplementary information
-
https://doi.org/10.1016/j.ijpharm.2018.10.014
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
4
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The paper proposes a methodology to determine the break force of pharmaceutical tablets. This is highly significant because the break force is an essential quality attribute logged on to the formal batch record during manufacturing. The batch record is traceable from the batch number printed on the packaging of every medicine sold. The methodology introduced in the paper is more accurate than the United States Pharmacopoeia (USP) method. USP standards are legally recognized in the U.S. and elsewhere, and are used in more than 140 countries to help ensure the quality, safety, and benefit of medicines and foods.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -