Impact of metal ions on PCR inhibition and RT-PCR efficiency
- Submitting institution
-
University of Dundee
- Unit of assessment
- 12 - Engineering
- Output identifier
- 54364019
- Type
- D - Journal article
- DOI
-
10.1007/s00414-020-02363-4
- Title of journal
- International Journal of Legal Medicine
- Article number
- -
- First page
- 63
- Volume
- 135
- Issue
- 1
- ISSN
- 0937-9827
- Open access status
- Compliant
- Month of publication
- July
- Year of publication
- 2020
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- 5 - Biological Sciences
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- Yes
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
2
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This paper provides foundational information relating to the underlying the methods used to analyse DNA in a forensic context where metal contamination of samples are a consideration. This also goes some way to addressing a current challenge in the recovery of DNA from metal surfaces (such as cartridge cases for example) where recovery rates are less than 10%. The work also begins to develop a comprehensive understanding of the science underpinning forensic science methods providing reassurance and clarity for legal proceedings.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -