Underwater Leidenfrost nanochemistry for creation of size-tailored zinc peroxide cancer nanotherapeutics
- Submitting institution
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University of Dundee
- Unit of assessment
- 12 - Engineering
- Output identifier
- 50579757
- Type
- D - Journal article
- DOI
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10.1038/ncomms15319
- Title of journal
- Nature Communications
- Article number
- 15319
- First page
- -
- Volume
- 8
- Issue
- -
- ISSN
- 2041-1723
- Open access status
- Compliant
- Month of publication
- May
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
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8
- Research group(s)
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-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Mimicking the volcano-induced dynamic chemistry of deep oceans, size-tailored, monodisperse anticancer nanoparticles can be synthesized in the lab. This advanced chemical approach, i.e. the Leidenfrost technique, enables formation of nanoclusters of zinc peroxide in a green manner. These nanoparticles perform as oxygen suppliers and therefore can be employed in treatment of various diseases induced by anaerobic and even cancerous cells. As proved in this study, zinc peroxide nanoparticles are able to kill tumor cells via apoptotic and non-apoptotic mechanisms. This work has been reported by various online magazines such as Space Daily and Science News line, among others.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -