A new mode of contrast in biological second harmonic generation microscopy
- Submitting institution
-
The University of Sheffield
- Unit of assessment
- 12 - Engineering
- Output identifier
- 5694
- Type
- D - Journal article
- DOI
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10.1038/s41598-017-13752-y
- Title of journal
- Scientific Reports
- Article number
- 13331
- First page
- -
- Volume
- 7
- Issue
- -
- ISSN
- 2045-2322
- Open access status
- Compliant
- Month of publication
- October
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
5
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This paper describes and evidences the first model for a new mode of biological imaging, showing the potential to derive previously inaccessible structural information. By resolving the disputed phenomenon, the method highlights the possibility for much improved imaging of biological samples to enhance patient health outcomes. It has underpinned two successful grant proposals (Reversing skin contraction in paediatric burns patients, Sheffield Hospitals Charity, 181902 £461,110 and Multi-materials additive manufacturing for musculoskeletal applications, £95,585 Royal Society IES\R3\183215); been included in a review of label free multi-harmonic imaging (doi.org/10.1063/1.5098349); and led to an invited presentation at SPIE Photonics Europe 2020.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -