A novel computational model predicts key regulators of chemokine gradient formation in lymph nodes and site-specific roles for CCL19 and ACKR4
- Submitting institution
-
Imperial College of Science, Technology and Medicine
- Unit of assessment
- 12 - Engineering
- Output identifier
- 295
- Type
- D - Journal article
- DOI
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10.4049/jimmunol.1700377
- Title of journal
- Journal of Immunology
- Article number
- -
- First page
- 2291
- Volume
- 199
- Issue
- 7
- ISSN
- 0022-1767
- Open access status
- Compliant
- Month of publication
- September
- Year of publication
- 2017
- URL
-
-
- Supplementary information
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10.4049/jimmunol.1700377
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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4
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- First quantification of the importance of lymph flow in guiding the migration of immune cells within lymph nodes. The work received a five-year grant from the Wellcome Trust (206284/Z/17/Z, £2M) for a new collaboration with the Universities of Nottingham and Glasgow, as well as a PhD studentship from the British Heart Foundation. It also resulted in invited keynote lectures at several international conferences including Conference of the European Society for Biomaterials, International Conference on Computational Science and NAVBO Lymphatics Forum.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -