A chronically-implantable neural coprocessor for investigating the treatment of neurological disorders
- Submitting institution
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University of Oxford
- Unit of assessment
- 12 - Engineering
- Output identifier
- 9420
- Type
- D - Journal article
- DOI
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10.1109/TBCAS.2018.2880148
- Title of journal
- IEEE Transactions on Biomedical Circuits and Systems
- Article number
- -
- First page
- 1230
- Volume
- 12
- Issue
- 6
- ISSN
- 1932-4545
- Open access status
- Compliant
- Month of publication
- November
- Year of publication
- 2018
- URL
-
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- Supplementary information
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- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
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12
- Research group(s)
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-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This system is a key component of the NIH BRAIN public-private partnership. More than five human use trials have been approved using this device, and first implants have already occurred in humans (see for example ClinicalTrials.gov Identifier: NCT03582891 (Dystonia and Parkinson's) and NCT03815656 (Parkinson's), NCT03946618 (epilepsy), NCT04281134 (OCD), NCT04106466 (depression). The sensing interface chip was added to the Medtronic Percept(TM) Brain Stimulation System, which is now CE-marked and FDA-approved for epilepsy, Parkinson's, essential tremor and obsessive-compulsive disorder. (Chief Medical Officer, Medtronic available to corroborate).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -