Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis
- Submitting institution
-
The University of Essex
- Unit of assessment
- 11 - Computer Science and Informatics
- Output identifier
- 1479
- Type
- D - Journal article
- DOI
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10.1038/s41467-020-16878-2
- Title of journal
- Nature Communications
- Article number
- 3097
- First page
- 3097
- Volume
- 11
- Issue
- 1
- ISSN
- 2041-1723
- Open access status
- Compliant
- Month of publication
- June
- Year of publication
- 2020
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
27
- Research group(s)
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A - Artificial Intelligence (AI)
- Citation count
- 9
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Nature Communications is among the top journals in inter-disciplinary research. This work demonstrates for the first-time that bone marrow adiposity (BMA) has distinct roles in human metabolism against other explored fat types, using PET, MRI, CT and transcriptomic analysis. With a significant number of downloads (>3,000) and being higher than 97% of ResearchGate items in downloads and interactions since its 2019 preprint (https://doi.org/10.1101/673129), this work is leading the field. This is the foundation publication for the MRC "OPTIMAT" project, a field-changing study on BMA using 100,000 MRI and 500,000 genetic data, which enrols world-leading scientists in the field (Cawthorn/Theodoratou,U.Edinburgh; Karampinos,TUM).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -