Electrochemical determination of microRNAs based on isothermal strand-displacement polymerase reaction coupled with multienzyme functionalized magnetic micro-carriers
- Submitting institution
-
Queen Mary University of London
- Unit of assessment
- 12 - Engineering
- Output identifier
- 578
- Type
- D - Journal article
- DOI
-
10.1016/j.bios.2015.12.064
- Title of journal
- Biosensors and Bioelectronics
- Article number
- -
- First page
- 344
- Volume
- 80
- Issue
- -
- ISSN
- 0956-5663
- Open access status
- Out of scope for open access requirements
- Month of publication
- December
- Year of publication
- 2015
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
7
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The study led to a collaboration with Nanfang Hospital at Southern Medical School, Guangzhou and a funded exchange visit (UK-GCRF). The visit enabled identification of promising lateral flow sampling and testing platforms for near patient clinical diagnostics. This established preliminary design work for simplified sampling for biosensors and led to a funded one year project for testing for neutralising patient antibodies against drug antibodies (Development of a bioluminescence assay probe: NIHR200325) as a joint project with a spinout company (Camstech Ltd). The work is continued in a 3 year project to produce a clinical device (i4i Connect, NIHR201645).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
