Safety and effectiveness of hormonal treatment versus hormonal treatment with vigabatrin for infantile spasms (ICISS): a randomised, multicentre, open-label trial
- Submitting institution
-
University of Southampton
- Unit of assessment
- 4 - Psychology, Psychiatry and Neuroscience
- Output identifier
- 35513739
- Type
- D - Journal article
- DOI
-
10.1016/S1474-4422(16)30294-0
- Title of journal
- The Lancet Neurology
- Article number
- -
- First page
- 33
- Volume
- 16
- Issue
- 1
- ISSN
- 1474-4422
- Open access status
- Compliant
- Month of publication
- November
- Year of publication
- 2016
- URL
-
-
- Supplementary information
-
https://ars.els-cdn.com/content/image/1-s2.0-S1474442216302940-mmc1.pdf
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
16
- Research group(s)
-
-
- Citation count
- 82
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- -
- Author contribution statement
- Kennedy - The (international) ICISS trial compared two treatments in a rare condition of infancy (infantile spasms) in an RCT, the standard treatment being the one that was more effective in the preceding (UK) UKISS trial. The design of both trials drew heavily on a preceding international RCT comparing two treatments for another rare condition of infancy (post-haemorrhagic ventricular dilation) in which I provided the design, secured the funding, and led. I also played a substantial role in the writing of the published manuscripts of the UKISS and ICISS trials.
- Non-English
- No
- English abstract
- -
