A synergistic effect of albumin and H2O2 accelerates corrosion of Ti6Al4V
- Submitting institution
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The University of Birmingham
- Unit of assessment
- 12 - Engineering
- Output identifier
- 24272624
- Type
- D - Journal article
- DOI
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10.1016/j.actbio.2015.07.046
- Title of journal
- Acta Biomaterialia
- Article number
- -
- First page
- 355
- Volume
- 26
- Issue
- -
- ISSN
- 1742-7061
- Open access status
- Out of scope for open access requirements
- Month of publication
- July
- Year of publication
- 2015
- URL
-
-
- Supplementary information
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-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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2
- Research group(s)
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-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This is the first paper to look at the combined effects of albumin (a major protein in the body) and peroxide on corrosion of a Ti implant alloy. It demonstrated that corrosion of implant alloys in the body may be more severe than that predicted by standard tests using physiological saline alone. This is likely to be a particular problem where there is local inflammation, for example during local infection when cells generate reactive oxygen species (simulated by peroxide). It has led to the observation by other groups of similar effects on other implant alloy systems and corrosion-resistant coatings.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -