A bio-inspired microstructure induced by slow injection moulding of cylindrical block copolymers.
- Submitting institution
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University of Cambridge
- Unit of assessment
- 12 - Engineering
- Output identifier
- 7282
- Type
- D - Journal article
- DOI
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10.1039/c4sm00884g
- Title of journal
- Soft Matter
- Article number
- -
- First page
- 6077
- Volume
- 10
- Issue
- 32
- ISSN
- 1744-6848
- Open access status
- Out of scope for open access requirements
- Month of publication
- -
- Year of publication
- 2014
- URL
-
-
- Supplementary information
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-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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6
- Research group(s)
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-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This paper demonstrates the formation by slow injection moulding of a novel bi-directional microstructure, mimicking the natural tissue of heart valves. This led directly to a BHF Special Project Grant (SP/15/5/31548, 755,030), resulting in the design and manufacture of polymeric prosthetic heart valves which have met all ISO standards for in vitro testing and are about to commence a small in vivo trial in sheep. The above grant introduced JS (an early career researcher) as a co-I on this project. The work described in the paper also led to patents WO2015128605-A1, EP3110463-A1 and US2017014546-A1, with priority date 27 Feb 2014.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -