Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model
- Submitting institution
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University of Oxford
- Unit of assessment
- 12 - Engineering
- Output identifier
- 9554
- Type
- D - Journal article
- DOI
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10.1093/brain/awx350
- Title of journal
- Brain
- Article number
- -
- First page
- 422
- Volume
- 141
- Issue
- 2
- ISSN
- 0006-8950
- Open access status
- Compliant
- Month of publication
- January
- Year of publication
- 2018
- URL
-
-
- Supplementary information
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https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/brain/141/2/10.1093_brain_awx350/2/supplementary_materials_awx350.pdf?Expires=1614247795&Signature=sPKHorVj5Qb7iRUyYpf93KMgpXA5ACcAe-zXOIPZY1DDRUx1SBOFPTg8fYIj2a8iBd~C22K9lA46FeKRCQmARO~1fqZKs3mk2UlR9xgtqYuSWSSeEWsgtX0RGVFEhh13ssfERkdklARmbTCLW2VYV8NFaQ~9JuGMGTxHuiqCiWqCwLDQVykp4cdtWkJ~l5UQdzx2sBtnWVzjaf05M648SogvNGtfu~zZ5S4xE4ztXu1C4Ojp~L5LLtLYs8kAWF1yUGQqhaSnSIHwIYI34BwUEc7VG9sQ2~HjsBRfum-3KjWhhF3A9NJ4lbnHIlHP5LhYCcTKrNti4usLGaskcPX5CA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
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45
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Reported in the leading neurology journal ('Brain'), this paper showed that impact to the head resulted in haemorrhage in brain tissue and concussion, in contrast to a 2012 paper which showed that blast-waves result in damage to memory without apparent trauma or concussion. Together these papers contrast the difference in mechanisms for persons exposed to blast-waves (e.g. soldiers close to an explosion) and direct impact (e.g. head impact in sports). These findings and their ramifications for sports, public health and military policy were reported by 169 news outlets including Forbes (https://www.forbes.com/sites/brucelee/2019/09/13/rob-gronkowski-said-that-he-fixed-his-cte-how-is-that-possible/) and New York Times (https://www.nytimes.com/2018/01/31/well/move/hits-to-the-head-may-result-in-immediate-brain-damage.html?emc=rss&partner=rss) with 1626 Altmetric score.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -