Paxman Scalp Cooling Cap for prevention of Chemotherapy -Induced-Alopecia
- Submitting institution
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The University of Huddersfield
- Unit of assessment
- 32 - Art and Design: History, Practice and Theory
- Output identifier
- 44
- Type
- T - Other
- DOI
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- Location
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- Brief description of type
- Multi-component: Articles and Patents including Contextual Information
- Open access status
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- Month
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- Year
- 2016
- URL
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- Supplementary information
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- Request cross-referral to
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- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
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- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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0
- Research group(s)
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- Proposed double-weighted
- Yes
- Double-weighted statement
- The long-standing multiphase collaboration between Dr Unver and Paxman Coolers commenced with the successful design, development and prototyping of a scalp-cooling cap to reduce chemotherapy-induced hair-loss (2012-2014). After extensive investigation a pioneering mass-manufacturing method was developed, innovatively integrating rapid-tooling and silicon-sheet forming (2014-2016). This success facilitated a scope-extension to address global variations in cranial morphology, generating a 3D-scan head-variation database, and ultimately developing an increased product-range suitable for patients globally (2015-2019). Alongside the internationally-successful award-winning product, multiple outputs have resulted, including 2 patents, 2 journal papers, 1 conference paper; and was presented by Dr Unver at 4 international conferences.
- Reserve for an output with double weighting
- No
- Additional information
- This multi-component output brings together multiple output types from an ongoing collaboration with Paxman Coolers Ltd, which commenced in 2012 and has ultimately generated an award-winning, patented medical scalp-cooling cap. The cap is commercially successful in 54 countries, achieving international regulatory approvals, including FDA (USA) and Shonin (Japan).
Scalp-cooling reduces/prevents chemotherapy-induced hair-loss in cancer patients. Hair-loss is one of the most traumatic chemotherapeutic side-effects, affecting annually 65,000 UK patients, and 3.12 million worldwide. The concept of scalp-cooling has been recognised for >40 years, but has presented significant challenges for manufacture.
These outputs including two patents, two journal papers, a peer-review conference paper and multiple exhibitions (citations above).
Dr E Unver led the design and development of the scalp-cooling cap, and revolutionised the cap manufacturing method using rapid tooling.
Preliminary research involved a thorough scoping exercise; reviewing scalp-cooling procedure, technical challenges, critical competitive analysis and patent reviews.
Anthropometric data was then analysed to establish head size/shape variance, and 3D laser scanning was used to create 3D-heads for 3D-CAD modelling. These were used for concept generation and development of the prototype.
The prototype was designed to optimise scalp-fit and uniform coolant-circulation, whilst providing high levels of patient comfort and adhering to medical regulations. Incorporation of manufacturing simplifications was imperative to the design, paving the way for future mass manufacture.
Various cap forms were evaluated, including optimisation of internal channel design for maximising scalp-contact and coolant flow. The final concept involved creating a flexible 3D-folded silicon cap.
For production, a novel method utilising 3D-laser sintering rapid tooling and twin-sheet silicone sheet thermoforming was developed, revolutionising cooling-cap production methods.
Two patents cover the cap design, the novel scalp-contact surface and the cap’s novel manufacturing process.
Whilst the collaboration commenced in 2012, none of this work was published prior to, or submitted to, REF 2014.
- Author contribution statement
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- Non-English
- No
- English abstract
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