Human cortical folding across regions within individual brains follows universal scaling law
- Submitting institution
-
University of Newcastle upon Tyne
- Unit of assessment
- 11 - Computer Science and Informatics
- Output identifier
- 257863-177336-1292
- Type
- D - Journal article
- DOI
-
10.1038/s42003-019-0421-7
- Title of journal
- Communications Biology
- Article number
- 191
- First page
- -
- Volume
- 2
- Issue
- -
- ISSN
- 2399-3642
- Open access status
- Compliant
- Month of publication
- May
- Year of publication
- 2019
- URL
-
https://doi.org/10.1038/s42003-019-0421-7
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
4
- Research group(s)
-
B - Interdisciplinary Computing and Complex Biosystems (ICOS)
- Citation count
- 2
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This provides provides understanding of the brain’s folded shape based on mathematical theory and computational geometry. We show that different parts of the brain obey the same universal scaling law as the whole brain. This is an important insight for using brain shape as a diagnostic tool in brain diseases, where e.g. some parts of the brain deviate from the scaling law. This work has been invited as a platform talk at SfN, the largest international neuroscience conference. After releasing the source code, several groups around the world currently using our code for their analyses.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -