3D Printing of Drug-Loaded Thermoplastic Polyurethane Meshes: A Potential Material for Soft Tissue Reinforcement in Vaginal Surgery
- Submitting institution
-
University of Ulster
- Unit of assessment
- 12 - Engineering
- Output identifier
- 78225258
- Type
- D - Journal article
- DOI
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10.3390/pharmaceutics12010063
- Title of journal
- Pharmaceutics
- Article number
- 63
- First page
- -
- Volume
- 12
- Issue
- 1
- ISSN
- 1999-4923
- Open access status
- Compliant
- Month of publication
- January
- Year of publication
- 2020
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
7
- Research group(s)
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C - Biomaterials and Tissue Engineering
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Polypropylene surgical meshes have represented the mainstay of treatment for pelvic organ disorders. However, the FDA warnings and the frequent complications (i.e. infection and erosion) following mesh implantation have forced healthcare systems worldwide to ban or suspend their use. This multi-institutional paper is significant for the research community because highlights the importance in combining 3D printing and functional biomaterials to develop novel patient-specific devices, with significantly enhanced antibacterial and tailorable biomechanical properties. It formed the foundation for a subsequent international project to produce 3D printed drug-loaded biodegradable implants (Mol. Pharmaceutics 2020, 17, 3487−3500) and a joint PhD scholarship.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -