Single-step detection of norovirus tuning localized surface plasmon resonance-induced optical signal between gold nanoparticles and quantum dots
- Submitting institution
-
University of Dundee
- Unit of assessment
- 12 - Engineering
- Output identifier
- 48742097
- Type
- D - Journal article
- DOI
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10.1016/j.bios.2018.09.024
- Title of journal
- Biosensors and Bioelectronics
- Article number
- -
- First page
- 16
- Volume
- 122
- Issue
- -
- ISSN
- 0956-5663
- Open access status
- Access exception
- Month of publication
- September
- Year of publication
- 2018
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- 8 - Chemistry
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
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8
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Noroviruses are the leading etiological viral agent of acute gastroenteritis and are the predominant causative agents of outbreaks of foodborne disease. This work reported on a single-step immunofluorescence detection of norovirus using a nanohybrid composed of gold nanoparticle and quantum dots. The nanobiosensor was 100-fold higher than commercial ELISA kit for norovirus and was highly selective over other tested viruses. The biosensor technology developed in this paper has been employed in a similar way to detect MERS-CoV (https://doi.org/10.1021/acssensors.9b00175) and this technology is currently been used to study SARS-CoV-2viral mechanisms of infection in order to identify targets for therapeutic intervention (https://doi.org/10.1021/acsnano.0c05975).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -