Adventitious match probability for autosomal profiles when primer binding site mutation is possible
- Submitting institution
-
Aston University
- Unit of assessment
- 11 - Computer Science and Informatics
- Output identifier
- 44903411
- Type
- D - Journal article
- DOI
-
10.1016/j.fsigen.2016.06.011
- Title of journal
- Forensic Science International: Genetics
- Article number
- -
- First page
- 143
- Volume
- 24
- Issue
- -
- ISSN
- 1872-4973
- Open access status
- Deposit exception
- Month of publication
- June
- Year of publication
- 2016
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
2
- Research group(s)
-
A - Aston Institute of Urban Technology and the Environment (ASTUTE)
- Citation count
- 0
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- In 2014, the National DNA Database introduced several DNA multiplex chemistries for loading and searching DNA profiles. Following a briefing on the new chemistries, the UK Judiciary requested an investigation on the effect which primer binding site mutations should have on the potential incidence of adventitious matches in cases where samples had been analysed using different chemistries. To address the Judiciary concerns, in this paper, new formulae describing adventitious match probabilities when primer binding site mutation is possible were derived algebraically and corroborated using computer simulations. The findings are also explained to the Judiciary in a dedicated paper (http://dx.doi.org/10.1016/j.scijus.2016.05.001).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
