Pluronic F127 thermosensitive injectable smart hydrogels for controlled drug delivery system development
- Submitting institution
-
The University of Bradford
- Unit of assessment
- 12 - Engineering
- Output identifier
- 60
- Type
- D - Journal article
- DOI
-
10.1016/j.jcis.2019.12.096
- Title of journal
- Journal of Colloid and Interface Science
- Article number
- -
- First page
- 119
- Volume
- 565
- Issue
- -
- ISSN
- 0021-9797
- Open access status
- Compliant
- Month of publication
- -
- Year of publication
- 2019
- URL
-
https://www.sciencedirect.com/science/article/pii/S0021979719315632?via%3Dihub
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
8
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Interdisciplinary work between pharmaceutics and engineering aiming to develop a safe, cost effective, easy to administer at room temperature, polymeric hydrogel for controlled drug release applications. Empirical formulae combining the coupled thermal and shear dependencies predict the behaviour during any processing stage and allow tailoring of the drug release profile. New understanding of structure-property relationships is presented through collaborative neutron and x-ray scattering with staff at RAL ISIS and Diamond Light Source. Three peer-reviewed STFC funded beamtime allocations contribute to the work which is being continued with surgeons at Leeds General Infirmary in applications for post-operative pain relief.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
