3D Printed Moulds Encompassing Carbon Composite Electrodes to Conduct Multi-Site Monitoring in the Entire Colon
- Submitting institution
-
University of Brighton
- Unit of assessment
- 12 - Engineering
- Output identifier
- 7140884
- Type
- D - Journal article
- DOI
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10.1021/acs.analchem.7b03148
- Title of journal
- Analytical Chemistry
- Article number
- -
- First page
- 11690
- Volume
- 89
- Issue
- -
- ISSN
- 0003-2700
- Open access status
- Compliant
- Month of publication
- October
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
3
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Most digestive disorders occur within the colon, and studies have shown using very small segments of the colon that mucosal signalling changes in these conditions. However, it is not well known if these small tissue segments are representative of signalling across the entire organ. This article is significant as it presents the first sensor for multisite measurement of signalling molecules over large regions. This technology enables the mapping of healthy and diseased tissue across the colon, and led to an EPSRC grant (EP/N027345/1) to implement this device for studies at leading US centres focused on bowel disorders.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -