Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer
- Submitting institution
-
University of Keele
- Unit of assessment
- 12 - Engineering
- Output identifier
- 393
- Type
- D - Journal article
- DOI
-
10.1038/s41598-017-05595-4
- Title of journal
- Scientific Reports
- Article number
- 5410
- First page
- -
- Volume
- 7
- Issue
- 1
- ISSN
- 2045-2322
- Open access status
- Compliant
- Month of publication
- July
- Year of publication
- 2017
- URL
-
https://www.nature.com/articles/s41598-017-05595-4/figures/
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
9
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This collaborative study between Keele and Imperial College resolved the controversy over the use of statins to help treat ovarian cancers via inhibition of a common tumour-promoting protein, TP53. The study was supported with studentship funding from the Iraqi Ministry of Higher Education and Scientific Research (MOHESR) (Keele) and Ovarian Cancer Action (Imperial College). National media recognised the study reach via BBC News and the Daily Mail and was widely re-blogged in the media. The study contributed to the successfully defended PhD thesis of Marwan Ibrahim Abdullah.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
