Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity.
- Submitting institution
-
Queen Mary University of London
- Unit of assessment
- 12 - Engineering
- Output identifier
- 593
- Type
- D - Journal article
- DOI
-
10.7554/eLife.18207
- Title of journal
- eLife
- Article number
- ARTN e18207
- First page
- e18207
- Volume
- 5
- Issue
- NOVEMBER2016
- ISSN
- 2050-084X
- Open access status
- Compliant
- Month of publication
- November
- Year of publication
- 2016
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
8
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- A collaboration between QMUL and University of Pennsylvania, part of a major multidisciplinary international collaboration (UK, USA, Germany) funded by a Human Frontier Science Program grant (RGP0025/2009-$1.2M) and an EU Marie Curie fellowship (301509-£151k). Led to successful funding applications (BBSRC project grant BB/N018532/1; NIH) and invited keynote presentations at Osteoarthritis Research Society International and EMBO Stem Cell Mechanobiology workshop. Part of a body of work that won the 2015 Orthopaedic Research Society’s prestigious Kappa Delta Young Investigator Award for co-author Mauck (https://www.aaos.org/CustomTemplates/Content.aspx?id=22803#2015). Contributed to PhD award for Heo and appointment to academic position for Thorpe (University College Dublin).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -