A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis
- Submitting institution
-
Queen Mary University of London
- Unit of assessment
- 1 - Clinical Medicine
- Output identifier
- 1853
- Type
- D - Journal article
- DOI
-
10.1016/j.jaci.2016.09.052
- Title of journal
- Journal of Allergy and Clinical Immunology
- Article number
- -
- First page
- 1228
- Volume
- 139
- Issue
- 4
- ISSN
- 0091-6749
- Open access status
- Compliant
- Month of publication
- April
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
13
- Research group(s)
-
A - Blizard
- Citation count
- 14
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- -
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -