An ultra scale-down method to investigate monoclonal antibody processing during tangential flow filtration (TFF) using ultrafiltration membranes.
- Submitting institution
-
University College London
- Unit of assessment
- 12 - Engineering
- Output identifier
- 12552
- Type
- D - Journal article
- DOI
-
10.1002/bit.26859
- Title of journal
- Biotechnol Bioeng
- Article number
- -
- First page
- 581
- Volume
- 116
- Issue
- 3
- ISSN
- 1097-0290
- Open access status
- Compliant
- Month of publication
- January
- Year of publication
- 2019
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
5
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Top downloaded paper in 2019. International co-author (JM Pollard, Merck & Co,. USA). This work led to another paper (https://doi.org/10.1016/j.memsci.2019.117606). The work was presented by the first author at the 3rd International Chemical Engineering 2017 and ACS National Meeting BIOT 2018. The device developed here was applied in an EngD on lentiviral vector (NIBSC and UCL Division of Infection and Immunity/2015-2019). The idea was further developed to establish an EPSRC-DTP PhD project (£80k/2020-24). This research formed the basis of a project on the optimisation of next-generation vaccines (£235K/UCL Coronavirus Response Fund with theEPSRC Vax-Hub).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
