Measurement of the inter-tablet coating uniformity of a pharmaceutical pan coating process with combined terahertz and optical coherence tomography in-line sensing
- Submitting institution
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The University of Lancaster
- Unit of assessment
- 12 - Engineering
- Output identifier
- 238288394
- Type
- D - Journal article
- DOI
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10.1016/j.xphs.2016.12.012
- Title of journal
- Journal of Pharmaceutical Sciences
- Article number
- -
- First page
- 1075
- Volume
- 106
- Issue
- 4
- ISSN
- 0022-3549
- Open access status
- Compliant
- Month of publication
- December
- Year of publication
- 2016
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
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6
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- We demonstrate for the first time spatial and temporal resolved measurements of the pharmaceutical coating process with terahertz and optical coherence tomography in-line sensing. The work underpins future process investigation and is the subject of an awarded EPSRC First Grant application (EP/R019460/1). This paper was one of the most downloaded and cited articles (https://www.journals.elsevier.com/journal-of-pharmaceutical-sciences/most-cited-articles) and is the subject to an invited talk at 2018 Compaction Simulation Forum. This work was performed in collaboration with Bosch Packaging Technologies, BASF and Coloron, where invited lectures at ‘Scale Up’ workshops were delivered (https://pharmablog.syntegon.com/2018/08/02/best-ratings-for-scale-up-seminar-at-huttlin-bosch/). It also led to a commercial system OCT-100 (http://www.szthz.org/index.php/Achievement-index-id-27.html).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
