Preferential Detachment During Human Brain Development: Age- and Sex-Specific Structural Connectivity in Diffusion Tensor Imaging (DTI) Data
- Submitting institution
-
University of Newcastle upon Tyne
- Unit of assessment
- 11 - Computer Science and Informatics
- Output identifier
- 196940-82336-1292
- Type
- D - Journal article
- DOI
-
10.1093/cercor/bht333
- Title of journal
- Cerebral Cortex
- Article number
- -
- First page
- 1477
- Volume
- 25
- Issue
- 6
- ISSN
- 1047-3211
- Open access status
- Compliant
- Month of publication
- June
- Year of publication
- 2015
- URL
-
http://dx.doi.org/10.1093/cercor/bht333
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
3
- Research group(s)
-
B - Interdisciplinary Computing and Complex Biosystems (ICOS)
- Citation count
- 53
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- As we grow older, our brains undergo a major reorganisation reducing the connections in the brain. We have demonstrated for the first time that the loss of fibres between brain regions is a highly selective process with preferential removal of short-distance connections. Furthermore, this refinement occurred earlier in girls than in boys which might explain their different maturation times during the teenager years and different likelihoods for the onset of neurodevelopmental disorders. This paper, following a press release, featured in several national and international newspapers (Daily Telegraph, Correio Braziliense, Correio do Estado, Dân Trí, 自由時報)
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
