CsrA maximizes expression of the AcrAB multidrug resistance transporter
- Submitting institution
-
The University of Birmingham
- Unit of assessment
- 12 - Engineering
- Output identifier
- 54942425
- Type
- D - Journal article
- DOI
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10.1093/nar/gkx929
- Title of journal
- Nucleic Acids Research
- Article number
- -
- First page
- 12798
- Volume
- 45
- Issue
- 22
- ISSN
- 0305-1048
- Open access status
- Compliant
- Month of publication
- October
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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4
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This multidisciplinary study reports on the development of a novel high throughput technique for identifying proteins responsible for regulation of gene expression in the context of antibiotic resistance and multidrug efflux. The technique is pivotal in one BBSRC grant application (currently under review) investigating gene expression leading to increased multidrug efflux with partners in Birmingham (J.Blair) and Quadram Institute (M.Webber). The collaboration with Blair in this area resulted in a further publication on a related technique (https://doi.org/10.3389/fmicb.2019.02319). Finally, this work showcased Overton’s expertise in the area and led to an invited talk at an Advanced Cytometry Course in Amsterdam (2019).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -