Improved cell infiltration of electrospun nanofiber mats for layered tissue constructs
- Submitting institution
-
The University of Bradford
- Unit of assessment
- 12 - Engineering
- Output identifier
- 12
- Type
- D - Journal article
- DOI
-
10.1002/jbm.a.35676
- Title of journal
- Journal of Biomedical Materials Research Part A
- Article number
- -
- First page
- 1479
- Volume
- 104
- Issue
- 6
- ISSN
- 1549-3296
- Open access status
- Out of scope for open access requirements
- Month of publication
- -
- Year of publication
- 2016
- URL
-
https://onlinelibrary.wiley.com/doi/abs/10.1002/jbm.a.35676
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
4
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Published in a leading journal in the field of biomedical research, this novel work details how smart architecture of biomaterials was used to manipulate cell orientation which helped organization of cells within 3D assembled nanofiber/cell constructs via nanofiber enabled cell layering. The findings have significant impact on the healing process of skin and ligaments/tendons as the smart architecture allow enough cell to penetrate inside the construct and provide full tissue regeneration which was major limitation. The research resulted from a collaboration between two research institutes in the USA and KSA and the outcome resulted in further funding (INSF-IR-113357 and Malaysia-FRGS5001).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
