Design, construction and characterisation of a novel nanovibrational bioreactor and cultureware for osteogenesis
- Submitting institution
-
University of the West of Scotland
- Unit of assessment
- 12 - Engineering
- Output identifier
- 14621118
- Type
- D - Journal article
- DOI
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10.1038/s41598-019-49422-4
- Title of journal
- Scientific Reports
- Article number
- 12944
- First page
- -
- Volume
- 9
- Issue
- 9
- ISSN
- 2045-2322
- Open access status
- Compliant
- Month of publication
- September
- Year of publication
- 2019
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
9
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Will revolutionise the provision of surgical bone graft - first induction-factor-free and scaffold-free demonstration of osteogenesis in a clinically approved collagen gel. Paper provided proof-of-principle that enabled two clinical trials to be funded (£2.8M SBCF funding for first-in-man surgical implant planned 2022, £396k STFC funding for first direct application to patients for treating osteoporosis starting 2019 for two years initially). Repeated coverage BBC Radio 4/5/World Service/Scotland (e.g. https://www.findabetterway.org.uk/news/extensive-bbc-coverage-synthetic-bone-project/) dedicated online articles (e.g. https://www.bbc.co.uk/news/uk-scotland-glasgow-west-46953192). Patients recruited in 2019 and treated in QEU Hospital Spinal Unit and provision of bioreactors to researchers and clinicians across UK (e.g. potential cancer therapies).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -